The topics faced in this book cover a large spectrum of current trends in mathematics, such as Shimura varieties and the Lang lands program, zonotopal combinatorics, non linear potential theory, variational methods in imaging, Riemann holonomy and algebraic geometry, mathematical problems arising in kinetic theory, Boltzmann systems, Pell's equations in polynomials, deformation theory in non commutative algebras. This work contains a selection of contributions written by international leading mathematicians who were speakers at the "INdAM Day", an initiative born in 2004 to present the most recent developments in contemporary mathematics.