PEGylated Protein Drugs: Basic Science and Clinical Applications
by Unknown
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Opis książki
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.
Szczegóły książki
Autor
Unknown
Wydawnictwo
Springer Basel
Rok wydania
2009
ISBN
9783764386795
Dostępne formaty
eBook (PDF, EPUB)
Audiobook (MP3)
Język
Polski